The influence of mineral dusts on metabolic co-operation between mammalian cells in tissue culture
- 1 January 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in Carcinogenesis: Integrative Cancer Research
- Vol. 3 (3) , 337-339
- https://doi.org/10.1093/carcin/3.3.337
Abstract
Carcinogenic UICC amosite asbestos has been tested in V79–4 cultures to determine whether it acts like a tumour promoter, such as TPA, by inhibiting metabolic co-operation. TPA inhibited metabolic co-operation at the non-toxic dose of 0.01 μg/ml but UICC amosite did not inhibit the cell to cell communication even at a toxic dose. Min-U-Sil silica and ballmilled amosite which were included as non-carcinogenic control dusts similarly did not inhibit metabolic co-operation.Keywords
This publication has 0 references indexed in Scilit: