Retinal function in birdshot retinochoroidopathy

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Abstract
The electroretinograms (ERGs) of 15 patients with birdshot retinochoroidopathy varied from supernormal to non‐recordable, depending upon the severity and the stage of the disease. The abnormal ERGs were characterized by a disproportionate decrease of the b‐wave amplitude compared with the a‐wave amplitude, demonstrating the negative (‐) type response. This distinct ERG pattern has not been observed in any other type of uveitis or chorioretinitis, and appears specific to birdshot retinochoroidopathy. ERG findings indicate that in birdshot retinochoroidopathy the neural layers of the retina are more diffusely and severely involved than the receptor‐retinal pigment epithelium‐choroid complex. In the most advanced stage, the patients becomes night blind with a non‐recordable ERG, a situation that is essentially the same as retinitis pigmentosa, except that pigmentation is conspicuously absent in the fundus.

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