Characteristic Magnetic Resonance Imaging Findings in Machado-Joseph Disease
Open Access
- 1 January 1998
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 55 (1) , 33-37
- https://doi.org/10.1001/archneur.55.1.33
Abstract
MACHADO-Joseph disease (MJD) is an autosomal dominant, multisystem, neurodegenerative disorder originally described in Portuguese-Azorean families.1-3 More recently, MJD has also been reported in non-Azorean families worldwide and is considered the most common type of autosomal dominant spinocerebellar degeneration.4-9 Advances in genetic analysis have made it possible to diagnose MJD more accurately.10 We clarified the characteristic magnetic resonance imaging (MRI) findings in patients with MJD diagnosed by genetic analysis.Keywords
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