Prostaglandins in Platelet Aggregation

Abstract
The inhibitory effect of different prostaglandins on ADP-induced platelet aggregation has been studied using a technique similar to that of Born and O'Brien. PGE 1 has a high inhibiting capacity while PGE 2 shows about one-fifth of that. The activity of the other prostaglandins investigated (PGE 1–217, PGF 2 α, PGF 1 β and PGF 1 α) is much lower.