SIGNIFICANCE OF NON-CONDYLOMATOUS WART VIRUS-INFECTION OF CERVICAL TRANSFORMATION ZONE - REVIEW WITH DISCUSSION OF 2 ILLUSTRATIVE CASES

  • 1 January 1978
    • journal article
    • research article
    • Vol. 22  (4) , 195-201
Abstract
The clinicopathologic features are described of 2 patients whose cervical cytology smears showed features which were thought initially to indicate dysplasia, but which were later considered to be those of condylomata acuminata. One patient was an immunosuppressed renal transplant recipient, the other was a routine gynecologic clinic patient. No condylomas were recognizable clinically, and colposcopy showed only a flat but atypical transformation zone. Biopsy in each case showed a noncondylomatous warty lesion and wart virus particles were demonstrated by EM. These cases highlight the clinical, colposcopic, cytologic and histologic diagnostic difficulties which are encountered with cervical transformation zone wart virus infections, which are commoner than formerly realized. The possible relationship of wart virus infection to cancer of the cervix is also discussed.