Successful production of transgenic rats
- 1 January 1990
- journal article
- research article
- Published by Taylor & Francis in Animal Biotechnology
- Vol. 1 (2) , 175-184
- https://doi.org/10.1080/10495399009525739
Abstract
DNA of pSV2‐gpt‐gE1A or SV2‐cat microinjected into pronuclei of fertilized rat eggs was found incorporated into chromosomes of 3 out of 48 (6.3%) or 10 out of 66 (15.2%) new born rats, respectively. The transgenic rats carrying SV2‐cat DNA transmitted the transgenes to their G1 progeny.Keywords
This publication has 12 references indexed in Scilit:
- Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 geneNature, 1990
- Genetransfer by pronuclear injection in the bovineTheriogenology, 1988
- Structures of integrated DNA containing human adenovirus E1A gene in transgenic mice.Agricultural and Biological Chemistry, 1988
- Introduction of human adenovirus E1A gene into fertilized mouse eggs.The Japanese journal of animal reproduction, 1987
- GERM-LINE TRANSFORMATION OF MICEAnnual Review of Genetics, 1986
- Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell AnemiaScience, 1985
- Production of transgenic mice, rabbits and pigs by microinjection into pronucleiReproduction in Domestic Animals, 1985
- Production of transgenic rabbits, sheep and pigs by microinjectionNature, 1985
- Genetic transformation of mouse embryos by microinjection of purified DNA.Proceedings of the National Academy of Sciences, 1980
- Fundamental study on the physiology of estrous cycle in the Wistar-Imamichi ratThe Japanese journal of animal reproduction, 1968