Complications and cardiovascular risk factors in South Asians and Europeans with early-onset type 2 diabetes

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Abstract
Background: Type 2 diabetes is a major cardiovascular risk factor, and early‐onset (Aim: To determine the prevalence of complications, and cardiovascular risk factors at diagnosis, in early‐onset type 2 diabetes, and to compare these between South Asians and Europeans. Design: Prospective study of newly‐diagnosed type 2 diabetes patients aged Methods: Patients were assessed for signs of macrovascular disease, retinopathy, neuropathy and nephropathy. Cardiovascular risk factors were also determined. Results: Overall, 292 patients were enrolled (165 South Asians). Macrovascular disease was more prevalent in South Asians (15.7% vs. 9.4%, pppppppDiscussion: Complications were common at diagnosis, with a quarter of all patients having evidence of at least one diabetic complication. South Asians had a higher prevalence of established macrovascular and microvascular disease, compared to Europeans, and a higher risk of CHD, predominantly because of lower HDL cholesterol and higher blood pressure.

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