PLASMA PROTEINS (ELECTROPHORETIC TECHNIC) IN NORMAL AND SHOCKED DOGS

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Abstract
Electrophoretic analyses of the plasma proteins of 34 dogs were made before and after a period of controlled hemorrhagic hypotension and, in many cases, shock. The more remote changes were studied 24 hrs. later. At the end of the period of hypotension, the total plasma protein was often greatly decreased, but no significant change in the relative concn. of the plasma protein fractions was noted. 24 hrs. later the total plasma protein had increased, in many instances returning to the normal level. In the animals in which more than 74% of the blood removed to produce hypotension was returned, the plasma protein pattern remained normal. The protein pattern of animals in which less than 75% of the blood withdrawn was returned showed elevated alpha2 and beta globulin concn.

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