THE ENDOCRINOLOGICAL EVALUATION OF BILATERAL AND UNILATERAL OOPHORECTOMY IN PREMENOPAUSAL WOMEN

  • 1 January 1983
    • journal article
    • research article
    • Vol. 28  (4) , 219-224
Abstract
The sequence of changes in serum FSH, luteinizing hormone (LH), prolactin (PRL), estradiol (E2), testosterone (T), and progesterone (P) levels immediately following unilateral and bilateral oophorectomy with hysterectomy, and hysterectomy alone, has been measured in 65 premenopausal women by radioimmunoassay (RIA). Relationship of vasomotor symptoms and serum hormone levels were studied and no correlation was found. The change of the relationship of the pituitary and gonadal hormones after castration is shown mathematically. Castration causes changes in the activity of the hypothalamo-pituitary and gonadal axis. Leaving at least 1 ovary to prevent postcastration symptoms and to maintain a good physiological condition is recommended.

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