Serum Polysaccharide Level in the Normal State.

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Abstract
Studies of serum polysaccharides were made on a group of normal persons including fetal, children, young adult and aged representatives. Serum polysaccharide detns. were made by a trypto-phan method, glucosamine by a modified method descr. in the paper, and total protein by a microkjeldahl method. Levels of serum polysaccharide and glucosamine associated with protein were significantly higher in young adults when compared to fetal representatives, but significantly lower when compared to aged persons. Significant positive correlations were found between nonglucosamine polysaccharide and total protein and between non-glucosamine polysaccharide and glucosamine. In the same individual serum polysaccharide and glucosamine levels were subject to about the same variation as serum polysaccharide over a period of 16 mos. Small variations in diet appeared to have little effect. No appreciable changes occurred during the menstrual cycle.

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