Calcium Homeostasis and Bone Metabolism

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Abstract
Parathyroid hormone and thyrocalcitonin act in opposite directions to provide the key elements in a reciprocal control system that guards calcium's availability. The former (with vitamin D) acts to stimulate bone resorption, the latter (with phosphate) to inhibit it. As the complexities of the system are worked out, the derangements occurring in certain bone diseases are becoming better understood.

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