Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer
Open Access
- 7 April 2005
- journal article
- Published by Springer Nature in Molecular Cancer
- Vol. 4 (1) , 1-14
- https://doi.org/10.1186/1476-4598-4-14
Abstract
Hsulf-1 is a newly identified enzyme, which has the ability to decrease the growth of hepatocellular, ovarian, and head and neck squamous cell carcinoma cells by interfering with heparin-binding growth factor signaling. Since pancreatic cancers over-express a number of heparin-binding growth factors and their receptors, the expression and function of this enzyme in pancreatic cancer was analyzed.Keywords
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