Quantitative Template for Subtyping Primary Progressive Aphasia
Open Access
- 1 December 2009
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 66 (12) , 1545-1551
- https://doi.org/10.1001/archneurol.2009.288
Abstract
The classification of primary progressive aphasia (PPA) into subtypes has acquired new relevance in light of postmortem series and in vivo amyloid imaging showing that individual variants have different likelihoods of being caused by Alzheimer disease (AD) vs frontotemporal lobar degeneration (FTLD). The most frequent associations have been reported between the agrammatic variant (PPA-G) and FTLD with tauopathy (FTLD-T), the semantic variant (PPA-S) and FTLD with ubiquitin/TAR-DNA binding protein 43 proteinopathy (FTLD-TDP), and the logopenic variant (PPA-L) and AD.1-3Keywords
This publication has 25 references indexed in Scilit:
- Neurology of anomia in the semantic variant of primary progressive aphasiaBrain, 2009
- The logopenic/phonological variant of primary progressive aphasiaNeurology, 2008
- Covert Processing of Words and Pictures in Nonsemantic Variants of Primary Progressive AphasiaAlzheimer Disease & Associated Disorders, 2008
- Aβ amyloid and glucose metabolism in three variants of primary progressive aphasiaAnnals of Neurology, 2008
- The Left Posterior Superior Temporal Gyrus Participates Specifically in Accessing Lexical PhonologyJournal of Cognitive Neuroscience, 2008
- Alzheimer and frontotemporal pathology in subsets of primary progressive aphasiaAnnals of Neurology, 2008
- Paradoxical features of word finding difficulty in primary progressive aphasiaAnnals of Neurology, 2005
- Cognition and anatomy in three variants of primary progressive aphasiaAnnals of Neurology, 2004
- Thresholding of Statistical Maps in Functional Neuroimaging Using the False Discovery RateNeuroImage, 2002
- The anatomy of language: contributions from functional neuroimagingJournal of Anatomy, 2000