Cyclic voltammetry of metal/polyelectrolyte complexes: Complexes of cadmium and lead with deoxyribonucleic acid

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Abstract
Cyclic voltammetry was used for the determination of the association constants of Pb2+and Cd2+with deoxyribonucleic acid. The adsorption of the biological polyelectrolyte at the mercury electrode surface was controlled by the alternating current voltammetric method, which permits corrective factors to be introduced in the evaluation of cyclic voltammetric responses. The results are based on the analysis of the labile complexation of the slow‐diffusing DNA by studying the current intensity peak as well as the peak potential shift of Pb2+and Cd2+. The association constants (β) obtained from the two treatments are in satisfactory agreement. The dependence of the conditional association constant (β1) for the Cd‐DNA system on the monovalent ion (Na+) concentration is also reported.