Studies on 2-oxoquinoline derivatives as blood platelet aggregation inhibitors. I. Alkyl 4-(2-oxo-1,2,3,4-tetrahydro-6-quinolyloxy)butyrates and related compounds.
- 1 January 1983
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 31 (3) , 798-810
- https://doi.org/10.1248/cpb.31.798
Abstract
Many alkyl 4-(2-oxo-1,2,3,4-tetrahydro-6-quinolyloxy)butyrates and related compounds were synthesized and tested for inhibitory activity against rabbit blood platelet aggregation in vitro. Among them, ethyl 4-(2-oxo-1,2,3,4-tetrahydro-6-quinolyloxy)butyrate had the most potent inhibitory activity. The structure-activity relationships are discussed.This publication has 8 references indexed in Scilit:
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