Analysis of the Interaction between the Transcription Factor σ G and the Anti-Sigma Factor SpoIIAB of Bacillus subtilis
Open Access
- 1 August 2003
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 185 (15) , 4615-4619
- https://doi.org/10.1128/jb.185.15.4615-4619.2003
Abstract
The activation of σG, a transcription factor, in Bacillus subtilis is coupled to the completion of engulfment during sporulation. SpoIIAB, an anti-sigma factor involved in regulation of σF, is also shown to form a complex with σG in vitro. SpoIIAA, the corresponding anti-anti-sigma factor, can disrupt the SpoIIAB:σG complex, releasing free σG. The data suggest the existence of an as-yet-unknown mechanism to keep σG inactive prior to engulfment.Keywords
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