Cytochrome P450 1B1 Expression in Glial Cell Tumors: An Immunotherapeutic Target
Open Access
- 15 June 2007
- journal article
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 13 (12) , 3559-3567
- https://doi.org/10.1158/1078-0432.ccr-06-2430
Abstract
Purpose: Among central nervous system malignancies, cytochrome P450 1B1 (CYP1B1) expression has only been characterized in medulloblastoma. An immunotherapeutic agent targeting this antigen was shown to safely stimulate a good immune response. To evaluate the viability of further research efforts targeting this antigen, we examined the expression of CYP1B1 in glial cell malignancies.Keywords
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