Homograft replacement of aortic valve and ascending aorta in a patient with non-specific giant cell aortitis.

Abstract
A case of giant cell aortitis causing ascending aortic aneurysm associated with aortic regurgitation is reported. The aneurysm was excised and the aortic valve replaced using a fresh homograft. The patient was followed up for 3 1/2 yr. There is good evidence of correction of the hemodynamic lesion and no evidence of further arteritis or aneurysmal formation. The pathological and clinical problems of this disease are discussed.