Effect of in vitro hemolysis on chemical values for serum.
- 1 November 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 24 (11) , 1966-1970
- https://doi.org/10.1093/clinchem/24.11.1966
Abstract
Hemolysis in serum specimens is commonplace. This study examines the effect of hemolysis on results of selected chemical assays. Hemolysis was simulated by adding hemolysate to serum to give hemoglobin concentrations of 90 to 2800 mg/liter and a rating by technologists of 0 to 4 + hemolyzed. The effect of hemolysis on values for some serum constituents, particularly acid phosphatase and creatine kinase, was shown to be method dependent. Not unexpectedly, hemolysis most affects results for lactate dehydrogenase.This publication has 10 references indexed in Scilit:
- A METHOD FOR THE RAPID DETERMINATION OF ALKALINE PHOSPHATASE WITH FIVE CUBIC MILLIMETERS OF SERUMPublished by Elsevier ,2021
- Creatine kinase in serum: 3. Further study of adenylate kinase inhibitors.Clinical Chemistry, 1977
- An evaluation of the Beckman chloride/carbon dioxide analyzer.Clinical Chemistry, 1976
- Creatine kinase in serum: 2. Interference of adenylate kinase with the assay.Clinical Chemistry, 1976
- The Effects of 0.1 and 1.0 PerCent Erythrocytes and Hemolysis on Serum Chemistry ValuesAmerican Journal of Clinical Pathology, 1976
- AN IMPROVED PROCEDURE FOR SERUM CREATINE PHOSPHOKINASE DETERMINATION1967
- Serum α-Hydroxybutyrate Dehydrogenase in DiagnosisJAMA, 1964
- Chemical and Diagnostic Specificity of Laboratory Tests: Effect of Hemolysis, Lipemia, Anticoagulants, Medications, Contaminants, and other VariablesAmerican Journal of Clinical Pathology, 1962
- A Modification of the Benzidine Method for Measurement of Hemoglobin in Plasma and UrineBlood, 1956
- A spectrophotometric method for the determination of creative phosphokinase and myokinaseBiochemical Journal, 1955