Abstract
Overuse injury (RSI) of the upper limb is a common and distinct clinical entity brought about by hard continuous use of the limb. Pain is felt in the muscles and joint ligaments whose biological tolerance has been exceeded; this tolerance varies individually and must be genetically determined. These structures are normally non-tender. Physical signs in overuse injury consist of tenderness in these injured structures. Such signs in the intrinsic muscles of the hand and ligaments of the wrist joint and carpometacarpal joint of the thumb are virtually diagnostic of overuse injury.

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