THE EFFECT OF HORMONE TREATMENT ON THE PHOSPHORYLASE ACTIVITY OF THE RABBIT UTERUS

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Abstract
Glycogen and phosphorylase activity were identified in the uterus of hormone treated rabbits. Glycogen granules were very abundant in both layers of the myometrium following estrogen stimulation. In the ovariectomized, progesterone or estrogen-progesterone treated animals only a small number of glycogen granules was detected in the myometrium. In the uteri of the rabbits treated with estrogen, phosphorylase activity was very intense in both layers of the myometrium. Only a trace of the enzyme was observed in the muscle layers of the animals treated with progesterone or with estrogen and progesterone. In the ovariectomized rabbits phosphorylase was observed in very small amounts in the outer part of the longitudinal layer.