Drugs from emasculated hormones: The principle of syntopic antagonism
- 1 June 1989
- journal article
- review article
- Published by Portland Press Ltd. in Bioscience Reports
- Vol. 9 (3) , 253-272
- https://doi.org/10.1007/bf01114681
Abstract
This lecture outlines the early stages in the discovery of adrenaline β-receptor antagonists and of the histamine H2-receptor antagonists. It ends with a brief personal view about future research.Keywords
This publication has 20 references indexed in Scilit:
- Pharmacological analysis of the pentagastrin‐tiotidine interaction in the mouse isolated stomachBritish Journal of Pharmacology, 1985
- An operational model of pharmacological agonism: the effect of E/[A] curve shape on agonist dissociation constant estimationBritish Journal of Pharmacology, 1985
- Modulation of Cell Adhesion during Induction, Histogenesis, and Perinatal Development of the Nervous SystemAnnual Review of Neuroscience, 1984
- Antagonism of an indirectly acting agonist: Block by propranolol and sotalol of the action of tyramien on rat heartEuropean Journal of Pharmacology, 1980
- Definition and Antagonism of Histamine H2-receptorsNature, 1972
- A NEW ADRENERGIC: BETA-RECEPTOR ANTAGONISTPublished by Elsevier ,1964
- CLINICAL PHARMACOLOGY OF A BETA-ADRENERGIC-BLOCKING AGENT (NETHALIDE)The Lancet, 1962
- PHARMACOLOGY OF A NEW ADRENERGIC BETA-RECEPTOR-BLOCKING COMPOUND (NETHALIDE)The Lancet, 1962
- A STUDY OF THE ADRENOTROPIC RECEPTORSAmerican Journal of Physiology-Legacy Content, 1948
- On some physiological actions of ergotThe Journal of Physiology, 1906