Acyl coenzyme A:cholesterol acyl transferase in macrophages utilizes a cellular pool of cholesterol oxidase-accessible cholesterol as substrate.
Open Access
- 1 January 1988
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 263 (3) , 1266-1272
- https://doi.org/10.1016/s0021-9258(19)57295-7
Abstract
No abstract availableThis publication has 18 references indexed in Scilit:
- Foam cell-forming J774 macrophages have markedly elevated acyl coenzyme A:cholesterol acyl transferase activity compared with mouse peritoneal macrophages in the presence of low density lipoprotein (LDL) despite similar LDL receptor activity.Journal of Clinical Investigation, 1987
- Transport of cholesterol from the endoplasmic reticulum to the plasma membrane.The Journal of cell biology, 1985
- Unmodified low density lipoprotein causes cholesteryl ester accumulation in J774 macrophages.Proceedings of the National Academy of Sciences, 1985
- LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in AtherosclerosisAnnual Review of Biochemistry, 1983
- Cholesterol movement between human skin fibroblasts and phosphatidylcholine vesiclesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1982
- Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol depositionProceedings of the National Academy of Sciences, 1979
- Role of acylcoenzyme A: Cholesterol o-acyltransferase in cholesterol metabolismProgress in Lipid Research, 1979
- The submicrosomal localization of acyl-coenzyme A–cholesterol acyltransferase and its substrate, and of cholesteryl esters in rat liverBiochemical Journal, 1978
- The Low-Density Lipoprotein Pathway and its Relation to AtherosclerosisAnnual Review of Biochemistry, 1977
- Receptor-dependent hydrolysis of cholesteryl esters contained in plasma low density lipoprotein.Proceedings of the National Academy of Sciences, 1975