Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome
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Open Access
- 1 July 2000
- journal article
- research article
- Published by Elsevier in The American Journal of Pathology
- Vol. 157 (1) , 277-286
- https://doi.org/10.1016/s0002-9440(10)64538-5
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (AG 10916, AG14762)
This publication has 70 references indexed in Scilit:
- Expression of β-Amyloid Precursor Protein-CD3γ Chimeras to Demonstrate the Selective Generation of Amyloid β1–40and Amyloid β1–42 Peptides within Secretory and Endocytic CompartmentsPublished by Elsevier ,1999
- Interaction of Cytosolic Adaptor Proteins with Neuronal Apolipoprotein E Receptors and the Amyloid Precursor ProteinJournal of Biological Chemistry, 1998
- Uptake and Internalization of Exogenous Apolipoprotein E3 by Cultured Human Central Nervous System NeuronsNeurobiology of Disease, 1998
- Presenilin 1 Regulates the Processing of β-Amyloid Precursor Protein C-Terminal Fragments and the Generation of Amyloid β-Protein in Endoplasmic Reticulum and GolgiBiochemistry, 1998
- Abnormalities in Alzheimer’s Disease Fibroblasts Bearing the APP670/671 MutationNeurobiology of Aging, 1997
- Cell and molecular neurobiology of presenilins: A role for the endoplasmic reticulum in the pathogenesis of Alzheimer's disease?Journal of Neuroscience Research, 1997
- Presenilins and Alzheimer diseaseNature Genetics, 1995
- The involvement of the small GTP-binding protein Rab5a in neuronal endocytosisNeuron, 1994
- Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset FamiliesScience, 1993
- Neuropathological stageing of Alzheimer-related changesActa Neuropathologica, 1991