Vergleich von Colchicin, Isocolchicin und Homologen auf ihre zellteilungshemmende Wirkung

Abstract
Using in vitro cultures of fibroblasts and mice ascites tumors, colchicine exhibits 1000 times the activity of iso-ethylcolchicine and 50 times that of isocolchicine. Ethylcolchicine was synthesized and found to be 4-5 times weaker than colchicine.

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