The pharmacokinetics of factor VIII and factor IX: methodology, pitfalls and applications

1 January 1997

journal article
Published by Wiley in Haemophilia

Vol. 3 (1) , 1-8
https://doi.org/10.1046/j.1365-2516.1997.00074.x

Abstract

This article reviews the pharmacokinetics of exogenous factor VIII and factor IX in patients with haemophilia. It focuses on the methodology (and inherent pitfalls) of pharmacokinetic studies, then summarizes available pharmacokinetic data and finally discusses some applications of pharmacokinetics for optimization of prophylactic treatment of haemophilia and for comparison of coagulation factor concentrates.

Keywords

COMPARATIVE STUDIES
DOSING
FACTOR VIII
FACTOR IX
METHODOLOGICAL ASPECTS
PHARMACOKINETICS.

This publication has 0 references indexed in Scilit: