Fluoride-Exchanging Resins for Caries Protection

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Abstract
Prototype anion-exchanging resins were used to treat artificial carious lesion; The resins penetrate into lesion porosity, harden, and release either F or Cl ions. After second demineralization, various histological features of the lesions were measured. I progression of untreated lesions, surface zones (SZ) decreased by 75% and lesion bodie increased by 86%, while in resin-treated lesions the SZ remained essentially constant ant lesion bodies increased by only 52%. Dark zones (DZ) of F resin-treated lesions wer significantly larger than the DZ of Cl resin-treated, untreated, and initial lesions. After initiation of lesions in sound enamel, the SZ was essentially the same for botl treated and untreated enamel but slightly larger lesion bodies developed in the treate( enamel. After demineralization, the DZ of F resin-treated enamel were significantly larger than in Cl resin-treated or untreated enamel. In a separate experiment the rate of phosphate release from demineralized enamel into i pH 4.5 buffer was decreased by 85% by a F resin treatment and by 41% by a Cl resin treatment. In summary, both resins act as a barrier to demineralization and the fluoride-releasing resin appears to promote remineralization during acid attack.

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