Budesonide for Inflammatory Bowel Disease -- Is It a Magic Bullet?

Publisher Website
Google Scholar
Abstract
Crohn's disease and ulcerative colitis are chronic, medically incurable inflammatory bowel diseases. Most patients with these disorders are treated at some point with systemic corticosteroids. The short-term response to corticosteroids may be gratifying, but the long-term effects can be so severe that the treatment is often worse than the disease.The ideal treatment for inflammatory bowel disease would therefore be a “magic bullet” that could induce clinical remissions as effectively as traditional corticosteroids without having as many side effects. For nearly 40 years, this principle has been used effectively in the topical therapy of distal colitis with hydrocortisone enemas. Many . . .