Serum Pentobarbital Assay by Capillary Electrophoresis
- 1 July 1993
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 16 (9-10) , 2059-2068
- https://doi.org/10.1080/10826079308019914
Abstract
A simple and rapid assay for pentobarbital in serum based on capillary electrophoresis (CE) is described. Serum is deproteinized with acetonitrile then electrophoresed at 11 KV in 300 mmol/L borate buffer pH 8.5. This method demonstrates the potential of CE for a rapid and simple quantitation of many drugs and small molecules in serum.Keywords
This publication has 3 references indexed in Scilit:
- Capillary ElectrophoresisScience, 1988
- High‐dose barbiturate therapy in humans: A clinical review of 60 patientsAnnals of Neurology, 1979
- Pentobarbital therapy for intracranial hypertension in metabolic coma Reyeʼs syndromeCritical Care Medicine, 1978