Differential Effects of Insulin on Brain Monoamine Metabolism in Rats
- 30 June 1983
- journal article
- research article
- Published by Wiley in Acta Pharmacologica et Toxicologica
- Vol. 53 (1) , 39-43
- https://doi.org/10.1111/j.1600-0773.1983.tb01865.x
Abstract
The effect of a subconvulsive dose of insulin, which caused a 70% reduction of plasma glucose levels, on catecholamine and 5-hydroxytryptamine turnover in different brain regions of rats was investigated. The turnover of norepinephrine was found to be increased in the hemispheres and that of 5-hydroxytryptamine was increased in the limbic forebrain and hemispheres, whereas the dopamine turnover was decreased in the striatum and limbic forebrain.Keywords
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