Salivary Gland Cancers, Surgery, and Irradiation Therapy

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Abstract
The concept of unique radioresistance of malignant salivary gland tumors has gradually disappeared. For years, occasional patients, usually those with unresectable tumors, were treated by irradiation alone or in combination with a surgical resection, on a very sporadic basis. Irradiation therapy did not become a vital part of the treatment until the past decade. The high rate of recurrence of some malignant salivary gland tumors after radical and very adequate operations dictated the necessity of considering an adjuvant therapy. The concept of preservation of function also played an important role in the search for treatment that improved local and regional control rates without unnecessary sacrifice of vital structures. Thus, irradiation therapy began to be used in an organized, systematic fashion in clinical situations other than for the palliative treatment of recurrent or unresectable tumors. It gradually became evident that the control rates could be improved remarkably in many clinical situations,

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