Treadmill training for the treatment of gait disturbances in people with Parkinson’s disease: a mini-review
- 4 November 2008
- journal article
- review article
- Published by Springer Nature in Journal Of Neural Transmission-Parkinsons Disease and Dementia Section
- Vol. 116 (3) , 307-318
- https://doi.org/10.1007/s00702-008-0139-z
Abstract
This report reviews recent investigations of the effects of treadmill training (TT) on the gait of patients with Parkinson’s disease. A literature search identified 14 relevant studies. Three studies reported on the immediate effects of TT; over-ground walking improved (e.g., increased speed and stride length) after one treadmill session. Effects persisted even 15 min later. Eleven longer-term trials demonstrated feasibility, safety and efficacy, reporting positive benefits in gait speed, stride length and other measures such as disease severity (e.g., Unified Parkinson’s Disease Rating Scale) and health-related quality of life, even several weeks after cessation of the TT. Long-term carryover effects also raise the possibility that TT may elicit positive neural plastic changes. While encouraging, the work to date is preliminary; none of the identified studies received a quality rating of Gold or level Ia. Additional high quality randomized controlled studies are needed before TT can be recommended with evidence-based support.Keywords
This publication has 86 references indexed in Scilit:
- The Effect of Exercise Training in Improving Motor Performance and Corticomotor Excitability in People With Early Parkinson's DiseaseArchives of Physical Medicine and Rehabilitation, 2008
- Treadmill exercise suppresses nigrostriatal dopaminergic neuronal loss in 6-hydroxydopamine-induced Parkinson's ratsNeuroscience Letters, 2007
- Effects of Treadmill Exercise on Dopaminergic Transmission in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Lesioned Mouse Model of Basal Ganglia InjuryJournal of Neuroscience, 2007
- Cueing training in the home improves gait-related mobility in Parkinson's disease: the RESCUE trialJournal of Neurology, Neurosurgery & Psychiatry, 2007
- The Evolution of Walking-Related Outcomes Over the First 12 Weeks of Rehabilitation for Incomplete Traumatic Spinal Cord Injury: The Multicenter Randomized Spinal Cord Injury Locomotor TrialNeurorehabilitation and Neural Repair, 2007
- Early Abnormalities of Vascular and Cardiac Autonomic Control in Parkinson’s Disease Without Orthostatic HypotensionHypertension, 2007
- Treadmill walking as an external pacemaker to improve gait rhythm and stability in Parkinson's diseaseMovement Disorders, 2005
- Falls in Parkinson's diseaseCurrent Opinion in Neurology, 2004
- Influence of dopaminergic medication on automatic postural responses and balance impairment in Parkinson's diseaseMovement Disorders, 1996
- Treadmill Training With Partial Body Weight Support Compared With Physiotherapy in Nonambulatory Hemiparetic PatientsStroke, 1995