Tumor-Targeted Gene Delivery Using Poly(Ethylene Glycol)-Modified Gelatin Nanoparticles: In Vitro and in Vivo Studies
- 8 June 2005
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 22 (6) , 951-961
- https://doi.org/10.1007/s11095-005-4590-3
Abstract
To develop safe and effective systemically administered nonviral gene therapy vectors for solid tumors, DNA-containing poly(ethylene glycol)-modified (PEGylated) gelatin nanoparticles were fabricated and evaluated in vitro and in vivo.Keywords
This publication has 33 references indexed in Scilit:
- Cellular Interactions and In Vitro DNA Transfection Studies with Poly(ethylene glycol)‐Modified Gelatin NanoparticlesJournal of Pharmaceutical Sciences, 2005
- Biodistribution and Targeting Potential of Poly(ethylene glycol)-modified Gelatin Nanoparticles in Subcutaneous Murine Tumor ModelJournal of Drug Targeting, 2004
- A vision for the National Cancer Program in the United StatesNature Reviews Cancer, 2004
- A tragic setbackNature, 2002
- Gene Therapy on TrialScience, 2000
- New horizonsAnti-Cancer Drugs, 1999
- Non-viral gene therapyCurrent Opinion in Biotechnology, 1994
- Gene Therapy Strategies for Treating Neoplastic DiseaseAnnals of the New York Academy of Sciences, 1994
- Biodegradable Long-Circulating Polymeric NanospheresScience, 1994
- Molecular trafficking across the nuclear pore complexCurrent Opinion in Cell Biology, 1992