Plant bZIP proteins gather at ACGT elements
- 1 February 1994
- journal article
- review article
- Published by Wiley in The FASEB Journal
- Vol. 8 (2) , 192-200
- https://doi.org/10.1096/fasebj.8.2.8119490
Abstract
ACGT cis-acting DNA sequence elements have been identified in a multitude of plant genes regulated by diverse environmental, physiological, and environmental cues. In vivo transient and transgenic plant expression studies have shown that these ACGT elements are necessary for maximal transcriptional activation. Plants possess a conserved family of DNA-binding proteins specific for these DNA sequence motifs. Well-defined in terms of nucleotide sequence required for protein/DNA interactions and transcriptional activation, various ACGT elements have been used as molecular probes to clone sequence-specific DNA binding proteins. All plant DNA-binding proteins specific for ACGT elements belong to the bZIP classification. Most recombinant bZIP proteins can interact with ACGT elements derived from different plant genes, albeit with different affinity. Systematic protein/DNA binding studies have shown that sequences flanking the ACGT core affect bZIP protein binding specificity. These studies have provided the basi...Keywords
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