Inverted terminal repetition in vaccinia virus DNA encodes early mRNAs
- 1 May 1980
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 285 (5759) , 21-25
- https://doi.org/10.1038/285021a0
Abstract
Vaccinia virus DNA contains a long inverted terminal repetition of MW .apprx. 6.8 .times. 106. A fragment of MW 6.3 .times. 106 from this repetition was cloned in coliphage .lambda. and used to isolate RNA from phage-infected [Escherichia coli] cells. EM indicates that early RNA are transcribed from the repeated sequence and cell-free translation shows that the RNA code for polypeptides.Keywords
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