Synthesis of the Taxol Derivatives: Control of Atropisomerism
- 1 January 1994
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1994 (08) , 584-586
- https://doi.org/10.1055/s-1994-22934
Abstract
An efficient synthesis of taxol derivatives was accomplished by the Lewis acid mediated intramolecular coupling of the dienol silyl ether and the acetal, in which controlling the atropisomerism of the cyclization precursor is crucial.Keywords
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