CAFFEINE ANTAGONIZES DIAZEPAM EFFECTS IN MAN

  • 1 January 1982
    • journal article
    • research article
    • Vol. 60  (2) , 121-123
Abstract
In a double-blind, placebo-controlled study on parallel groups of medical students, diazepam 10 mg impaired cognitive skills and caused relaxation. A 250-mg dose of caffeine given in decaffeinated coffee counteracted these effects better than a 500-mg dose. Subjectively, diazepam exerted a calming effect which was counteracted by caffeine at either dose level.