Meningococcal Disease in the United States--1986

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Abstract
Active surveillance for invasive meningococcal disease was conducted during 1986 and 1987 in six areas of the United States with a total population of ∼34 million persons. The incidence of meningococcal disease was 1.3:105. The highest incidence of disease among the surveillance areas was in Los Angeles County (1.65:105). Neisseria meningitidis serogroups Band C caused about equal amounts of disease, which reflects a recent increase in the incidence of group C disease. Group C caused more than half of the cases of meningococcal disease in Los Angeles and Tennessee but less than one-third of the cases in Missouri and Oklahoma. Multilocus enzyme electrophoresis demonstrated that a group of closely related isolates of N. meningitidis was prevalent in Los Angeles during the surveillance period and was associated with an increased incidence of meningococcal disease there.

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