Plasma Concentrations of Platelet-Specific Proteins in Coronary Artery Disease

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Abstract
The plasma concentrations of β-thromboglobulin (β-TG) and platelet factor 4 (PF4) were measured in 100 patients with documented coronary artery disease (CAD) and in 40 controls. 18 patients had had coronary artery bypass surgery (CABS), 25 patients were on therapy with β-blocking agents and 19 were treated with oral anticoagulants. 38 patients with CAD received neither CABS nor β-blocking or anticoagulating drugs. The highest plasma concentrations of β-TG and PF4 were found in the patient group without medical or surgical treatment (patients versus controls: p

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