Ionic Mechanisms of Cholinergic Excitation in Molluscan Neurons
- 23 June 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 156 (3782) , 1597-1599
- https://doi.org/10.1126/science.156.3782.1597
Abstract
Acetylcholine appears to be an excitatory transmitter at synapses on two different types of molluscan nerve cells: the so-called D - and CILDA neurons. The action of this substance is different in the two cases. In D -neurons, this compound increases the permeability of the subsynaptic or somatic membrane to chloride ions, and through a net efflux of this anion, depolarizes the cell. In CILDA neurons, on the other hand, acetylcholine depolarzies the cell by increasing its permeability to sodium ions.This publication has 12 references indexed in Scilit:
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