DDT: A New Hypothesis of Its Mode of Action
- 30 October 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 146 (3644) , 657-658
- https://doi.org/10.1126/science.146.3644.657
Abstract
It is suggested that DDT and perhaps other chlorinated hydrocarbon insecticides owe their activity to the formation of a charge-transfer complex with a component of the nerve axon, with consequent disturbance of function. Experimental evidence is provided for the formation of two complexes with components of cockroach nerve; the complexes have been partially purified. Their formation is accompanied by an absorption in the 245- to 270-millimicron range.Keywords
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