CX-659S, a Diaminouracil Derivative, Indirectly Inhibits the Function of Langerhans Cells by Blocking the MEK1/2-Erk1/2 Pathway in Keratinocytes
- 1 June 2003
- journal article
- Published by Elsevier in Journal of Investigative Dermatology
- Vol. 120 (6) , 983-989
- https://doi.org/10.1046/j.1523-1747.2003.12250.x
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- UVB-mediated activation of p38 mitogen-activated protein kinase enhances resistance of normal human keratinocytes to apoptosis by stabilizing cytoplasmic p53Biochemical Journal, 2002
- MAP Kinases in the Immune ResponseAnnual Review of Immunology, 2002
- A Critical Role for p38 Mitogen-Activated Protein Kinase in the Maturation of Human Blood-Derived Dendritic Cells Induced by Lipopolysaccharide, TNF-α, and Contact SensitizersThe Journal of Immunology, 2001
- TNF-α Induction by LPS Is Regulated Posttranscriptionally via a Tpl2/ERK-Dependent PathwayCell, 2000
- A role for NF-κB–dependent gene transactivation in sunburnJournal of Clinical Investigation, 2000
- Immunobiology of Dendritic CellsAnnual Review of Immunology, 2000
- MEK inhibitors: The chemistry and biological activity of U0126, its analogs, and cyclization productsBioorganic & Medicinal Chemistry Letters, 1998
- Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase KinaseJournal of Biological Chemistry, 1998
- Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB SynthesisScience, 1995
- The skin immune system: progress in cutaneous biologyImmunology Today, 1993