Cytogenetic findings in over 2000 amniocenteses.
- 15 October 1983
- journal article
- Vol. 129 (8) , 846-50
Abstract
Between 1971 and 1981, 58 (2.8%) of 2037 amniocenteses performed in Vancouver revealed chromosome abnormalities, 25 of which were trisomy 21. Of the 58 referrals that yielded abnormalities, 37 (63.8%) were for a maternal age of 38 years or more. The rates of detection of such abnormalities for single-year intervals of maternal age beyond 35 years were comparable to those calculated from pooled data obtained in multicentre studies in the United States, Canada and Europe.This publication has 21 references indexed in Scilit:
- Prenatal diagnosis in 3,000 women for chromosome, X‐linked, and metabolic disordersAmerican Journal of Medical Genetics, 1982
- Prenatal Diagnosis of Chromosomal Abnormalities: Analysis of 1000 Consecutive Amniotic FluidsAustralian and New Zealand Journal of Obstetrics and Gynaecology, 1981
- Risk of amniocentesis and laboratory findings in a series of 1500 prenatal diagnosesPrenatal Diagnosis, 1981
- Amniocentesis in the West Midlands: report on 1000 birthsJournal of Medical Genetics, 1980
- Chromosome findings in 2,500 second trimester amniocentesesAmerican Journal of Medical Genetics, 1980
- Prenatal Genetic Diagnosis in 3000 AmniocentesesNew England Journal of Medicine, 1979
- Down syndrome and recent demographic trends in Manitoba.Journal of Medical Genetics, 1978
- Incidence study of Down's syndrome in Copenhagen, 1960–1971: with chromosome investigationAnnals of Human Genetics, 1976
- CHROMOSOME ABNORMALITIES AND MATERNAL AGEThe Lancet, 1976
- PROSPECTIVE DATA ON RISK OF DOWN SYNDROME IN RELATION TO MATERNAL AGEThe Lancet, 1976