Effects of petroleum hydrocarbon solvents on alkaline phosphatase of rats

1 January 1978

journal article
Published by Springer Nature in Bulletin of Environmental Contamination and Toxicology

Vol. 19 (1) , 287-294
https://doi.org/10.1007/bf01685800

Abstract

After administration of benzene, gasoline, IOMEX or petroleum ether, liver alkaline phosphatase showed over 200% increase in activity whereas kidney alkaline phosphatase activity was depressed by 50%. The pattern of separation of isoenzymes of alkaline phosphatase in liver, kidney and serum indicated involvement of one of the isoenzymes. A simple method of detecting the incipent toxicity is described.

Keywords

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