Methionine-Enkephalin Inhibits Stress-Induced Increases in Noradrenaline Turnover in Brain Regions of Rats
Open Access
- 1 January 1985
- journal article
- Published by Elsevier in The Japanese Journal of Pharmacology
- Vol. 37 (1) , 117-119
- https://doi.org/10.1254/jjp.37.117
Abstract
Met-Enkephalin injected i.c.v. attenuated stress-induced increases in levels of 3-methoxy-4-hydroxyphenylethyleneglycol sulfate, the major metabolite of brain noradrenaline, in the hypothalamus, amygdala, hippocampus, thalamus, midbrain and LC region in rats. The data suggest that Met-enkephalin acts to attenuate stress-induced increases in noradrenaline turnover in these brain regions in rats.Keywords
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