Cytoplasmic inclusion bodies in Leydig cells from the testes of postpubertal cryptorchid patients

Abstract
During the course of EM studies on testes from cryptorchid patients, an inclusion body was observed in the cytoplasm of Leydig cells. Such inclusion bodies were detected in Leydig cells of postpubertal patients (16-30 yr), but were not evident in the cells of pubertal and prepubertal patients (3-12 yr); they also were not evident in cells from the contralateral descended scrotal testes of cryptorchid patients or in cells from normal controls. These inclusion bodies are therefore believed to result from specific cytological changes which occur in cryptorchid testes during puberty.