In Vivo Gene Transfer of the O 2 -Sensitive Potassium Channel Kv1.5 Reduces Pulmonary Hypertension and Restores Hypoxic Pulmonary Vasoconstriction in Chronically Hypoxic Rats
- 22 April 2003
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 107 (15) , 2037-2044
- https://doi.org/10.1161/01.cir.0000062688.76508.b3
Abstract
Background— Alveolar hypoxia acutely elicits pulmonary vasoconstriction (HPV). Chronic hypoxia (CH), despite attenuating HPV, causes pulmonary hypertension (CH-PHT). HPV results, in part, from inhi...Keywords
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