Keratitis from Misuse of Corneal Anesthetics
- 22 August 1968
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 279 (8) , 396-399
- https://doi.org/10.1056/nejm196808222790802
Abstract
Five cases are presented to emphasize the fact that chronic use of topical anesthetics on the eye can lead to severe keratitis and even permanent reduction of visual acuity. These reactions can be evoked in any eye that has been subjected to prolonged topical anesthesia as a means of relieving the discomfort of minor injuries. Loss of corneal epithelium (with resultant increased reliance on the anesthetic), opacification and edema of the corneal stroma and marked inflammatory changes in the anterior segment of the eye is the sequence of events that follow days or weeks of such treatment. Topical anesthetics should only be used for the purpose of obtaining transient loss of corneal sensitivity and never as part of a prolonged medical regimen.Keywords
This publication has 13 references indexed in Scilit:
- Demonstration of axonal flow by the movement of tritium-labeled protein in mature optic nerve fibers.Proceedings of the National Academy of Sciences, 1965
- OPHTHAINE (PROPARACINE HYDROCHLORIDE): A LOCAL ANAESTHETIC FOR OPHTHALMIC SURGERYBritish Journal of Ophthalmology, 1964
- The Trophic and Plastic Properties of SynapsesPublished by Springer Nature ,1964
- The part played by cerebral anaemia in the response to occlusion of the common carotid arteries in the catThe Journal of Physiology, 1963
- Desiccation of Cornea and Conjunctiva After Sensory DenervationArchives of Ophthalmology (1950), 1962
- Interactions between motoneurones and muscles in respect of the characteristic speeds of their responsesThe Journal of Physiology, 1960
- Taste buds on the cat's circumvallate papilla after reinnervation by glossopharyngeal, vagus, and hypoglossal nervesThe Anatomical Record, 1958
- The effects of glossopharyngeal nerve transection on the circumvallate papilla of the ratThe Anatomical Record, 1957
- Experimental Study of Corneal Lesions* *This work was done at the Experimental Institute of the Medical School of Porto Alegre.American Journal of Ophthalmology, 1956
- Ophthaine®American Journal of Ophthalmology, 1953