EFFICACY OF RESERPINE (SERPASIL) IN DERMATOLOGICAL THERAPY
- 1 December 1954
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 70 (6) , 713-717
- https://doi.org/10.1001/archderm.1954.01540240019002
Abstract
RESERPINE (Serpasil) represents a pure crystalline alkaloid of Rauwolfia serpentina, a small shrub indigenous to India. The roots of this plant had been used medicinally in Europe over 300 years ago for the treatment of anxiety states.1 In 1933, its value as a hypotensive agent was reported by a group of Indian investigators.2 Reserpine, thought to be the most important of the serpentine alkaloids, was first isolated in 1952 in Switzerland. Among the pharmacological effects noted was a quietude and reduction of emotional response.3 At a conference on resperine and other alkaloids of Rauwolfia serpentina presented by the New York Academy of Sciences on Feb. 5, 1954, many aspects of the clinical value of this drug were discussed. In addition to its value as an antihypertensive agent, Wilkens4 reported on the increased sense of well-being produced and on the ability of the drug to decrease neuroticKeywords
This publication has 0 references indexed in Scilit: