Paecilomyces variotii central nervous system infection in a patient with cancer
- 14 February 2003
- Vol. 46 (1-2) , 45-50
- https://doi.org/10.1046/j.1439-0507.2003.00837.x
Abstract
Paecilomyces variotii was isolated from two subsequent cerebrospinal fluid (CSF) specimens of a cancer patient. Identification was confirmed through beta-tubulin and rDNA ITS sequencing. MICs were determined for seven antifungal agents; the isolate was found to be susceptible to amphotericin B (AMB), itraconazole (ITZ), ketaconazole (KTZ) and 5-fluorocytosine (5FC) but resistant to fluconazole (FLZ) and miconazole (MCZ). Despite antimycotic therapy, the infection proved to be fatal.Keywords
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